MANAGEMENT OF ESSENTIAL HYPERTENSION, ISOLATED SYSTOLIC HTN AND MILD TO MODERATE HYPERTENSION
Adult:
(Peridopril/indapamide 2/0.625mg) one tab once daily in the morning before the meal. The dose may be doubled, if the BP control is unsatisfactory.
Precautions
Impaired renal function, risk of hypotension and electrolyte imbalance. Regular monitoring of plasma levels of K should be carried out, pregnancy, lactation.
Adverse Drug Reactions
Cough, headache, bradycardia, dizziness, asthenia, hypokalaemia and orthostatic hypotension.
Interactions
Lithium, K sparing diuretics, anaesthetics, cytostatic and immunosupressant agents and non-antiarrhythmic drugs should not be co-administered with perindopril/indapamide because of the potential for significant drug interactions with either component of the combined dose.